Showing posts with label hubs. Show all posts
Showing posts with label hubs. Show all posts

Friday 5 September 2014

The worst Ebola epidemic in history and the world is losing the battle to contain it

Ebola is one of those diseases that should scare us.  Especially this latest one in Western Africa. The graphs of the growing intensity of this disease has indicated frightening trends.


It has been 35 weeks since its outbreak and it is worrying to hear Medicine San Frontiers announce as it did so emphatically and publicly recently,

“Six months into the worst Ebola epidemic in history, the world is losing the battle to contain it,” said Dr. Liu. “Leaders are failing to come to grips with this transnational threat. The WHO announcement on August 8 that epidemic constituted a ‘public health emergency of international concern’ has not led to decisive action, and states have essentially joined a global coalition of inaction,” she said.

(MSF International President Dr. Joanne Liu)

she went on to stress

“States with the required capacity have a political and humanitarian responsibility to come forward and offer a desperately needed, concrete response to the disaster unfolding in front of the world’s eyes. Rather than limit their response to the potential arrival of an infected patient in their countries, they should take the unique opportunity to actually save lives where immediately needed, in West Africa.” 

This outbreak has spread from Guinea to Liberia, to Nigeria, Senegal and Sierra Leone.  The map of Western Africa shows how geographically this looks. 
and it does not look good.

“The clock is ticking and Ebola is winning,” said Dr. Liu. “The time for meetings and planning is over.  It is now time to act. Every day of inaction means more deaths and the slow collapse of societies.”

“Every day we have to turn sick people away because we are too full”, said Stefan Liljegren, the MSF coordinator at ELWA 3.  “I have had to tell ambulance drivers to call me before they arrive with patients, no matter how unwell they are, since we are often unable to admit them.”
MSF’s care centers in Liberia and Sierra Leone are overcrowded with suspected Ebola patients. People continue to become ill and are dying in their villages and communities. In Sierra Leone, highly infectious bodies are rotting in the streets.


These guys are on the front line and if they say we are losing the war then we should listen, for many moral and also totally selfish reasons.  The Ebola virus is so deadly that normally restricts its ability to spread among a population.  But this latest outbreak in Western Africa shows little sign of abating.  Looking at the WHO map, in its statement today the degree of the outbreak becomes clear. 


Most people are infected by giving care to other infected people, either by directly touching the victim's body or by cleaning up body fluids (stools, urine or vomit) that carry infectious blood.


Traditional African burial rituals have also played a part in its spread. The Ebola virus can survive for several days outside the body, including on the skin of an infected person, and it's common practice for mourners to touch the body of the deceased. They only then need to touch their mouth to become infected.

However, a recent paper (http://jid.oxfordjournals.org/content/196/Supplement_2/S142.full) has shown that the virus can be found as long as 61 days after original illness in the semen of patient.  This means that sex after recovery, for a period of months, can still spread the disease.  This is worrisome as the recent areas where the disease has been found are hubs of international travel.  Also, since the incubation of the Ebola virus can take 2-21 days it is possible that a person could climb on a plane not showing symptoms and then develop them subsequently and be contagious on arrival at their destination, spreading the outbreak globally.  In the west we are better at isolating and treating the victims, our nursing practices help stop infection spreading so easily but in today’s world of interconnectivity the importance of these travel hubs cannot be overestimated.


Just in case you think that this is impossible some one has already worked out estimates of numbers predicted in various countries if via these hubs the disease spreads.  

Not nice to see these graphs at all.  Mind you it all assumes that spread of Ebola by air routes is possible.  After all most of the people who are contagious are often bleeding and vomiting, pretty easy to spot, you'd think.  Unfortunately,  it has already happened.  The first case in Nigeria was reported by the WHO on 25 July: Patrick Sawyer, a Liberian Ministry of Finance official, flew from Liberia to Nigeria after exposure to the virus, and died at Lagos soon after arrival. In response, the hospital where he was being treated was shut down and quarantined, and the health officials who were treating him were isolated in an attempt to stop the spread of the virus. However, a doctor and nurse who treated Sawyer both died from Ebola.  Nigeria’s outbreak has arisen because of this one individual catching a plane.

In addition, there could be something worryingly different about this virus. “Scientists from the Broad Institute and Harvard University, in partnership with the Sierra Leone Ministry of Health and Sanitation, may have uncovered clues that set this Ebola outbreak apart from previous outbreaks. For this study, 99 Ebola virus genomes were collected and sequenced from 78 patients diagnosed with the Ebola virus during the first 24 days of the outbreak in Sierra Leone. The team found more than 300 genetic changes that make the 2014 Ebola virus distinct from previous outbreaks. It is still unclear whether these differences are related to the severity of the current outbreak. Five members of the research team became ill and died from Ebola before the study was published in August.” 

Given the presence of internal travel hubs effected by this present outbreak, Ebola’s high mortality rate, the chances of it spreading internationally and our own moral responsibility we should be fighting this virus with energy and commitment not inaction.

Whether this outbreak is contained in the next few months or not, it is a valuable exercise in how we can respond to such viruses in future events.  So far we are looking rather ineffectual and sluggish.  There is a lot going on at present on the global stage, Ukraine, Syria, Iraq etc and it is easy to see how a few thousand deaths in Africa don’t appear on the radar.  The Spanish flu came in the midst of a World War and killed 50 to 100 million people—three to five percent of the world's population.  This Ebola virus does not spread as easily but the Spanish Flu had a mortality rate of 2.5% whereas this Ebola virus can have a mortality rate of 50-90%. It’s time we united to fight this disease for those suffering and dying in Africa and for ourselves.